Which gender is more commonly affected by hemophilia?

Hemophilia is a genetic disorder that primarily affects the ability of blood to clot, leading to excessive bleeding. The gene responsible for hemophilia is located on the X chromosome. Since males have only one X chromosome (XY), if they inherit the defective gene, they will express the disorder. In contrast, females have two X chromosomes (XX). For a female to express hemophilia, she must inherit two copies of the defective gene, one from each parent, making it less likely for females to be affected compared to males. As a result, the prevalence of hemophilia is significantly higher in males, as they are more likely to exhibit the disorder given their single X chromosome.