Which event occurs during prophase of mitosis?

During prophase of mitosis, one of the key events that occurs is the condensation of chromosomes, along with the disintegration of the nuclear envelope. This is a crucial step in cell division, as it prepares the genetic material for the alignment and separation that will occur in the later stages of mitosis.

As chromosomes condense, they become visible under a microscope, which is essential for identifying any potential chromosomal abnormalities. The disappearance of the nucleus signifies that the cellular machinery is preparing to segregate the DNA into two daughter cells. This process marks the transition from interphase, where the cell is not dividing and the DNA is in a less condensed, more accessible form, to the actively dividing state of mitosis.

The focus on this event highlights the importance of prophase in setting up the subsequent stages of mitosis, where the proper separation of chromosomes is critical for maintaining genetic integrity in the daughter cells.